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Seroflo 250 multihaler is a blend of two prescriptions: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator that works by loosening up the muscles in the aviation routes and broadens the aviation routes. It is a steroid. It works by halting the arrival of certain compound couriers that irritate the aviation routes. Together, they make breathing simpler.